Patents:

1. P. R. Thompson, S. Mondal, "INHIBITORS OF PROTEIN ARGININE DEIMINASE 1 AND METHODS OF PREPARATION AND USE THEREOF" International Patent, WO2021/003078 A1.

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2. K. Fitzgerald, H. Fiachra, L. Galia, P. R. Thompson, S. Mondal, ‘TARGETING OF STING FOR THE TREATMENT OF INFLAMMATORY DISEASES’ US Patent, Application Serial No. 63/147,387.

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3. P. R. Thompson, S. Mondal, ‘PHOTOCAGED CITRULLINE ANALOGS AND METHODS FOR SITE-SPECIFIC INCORPORATION OF CITRULLINE INTO PROTEINS’ US Patent, Application Serial No. 63/161,918.

Publications:

34. Priyanka,# B. Raymandal,# S. Mondal* 'Native State Stabilization of Amyloidogenic Proteins by Kinetic Stabilizers: Inhibition of Protein Aggregation and Clinical Relevance' ChemMedChem, 2024, 10.1002/cmdc.202400244.

​

33. F. Humphries, L. Shmuel-Galia, Z. Jiang, J. Y. Zhou, L. Barasa, S. Mondal, R. Wilson, N. Sultana, S. A. Shaffer, S.-L. Ng, G. S. Pesiridis, P. R. Thompson, K. A. Fitzgerald, 'Targeting STING oligomerization with small-molecule inhibitors' Proceedings of the National Academy of Sciences, 2023, 120, e2305420120.

​

32. D. Giri, S. Mondal, G. Mugesh, 'Chemical Biology of Thyroid Hormones' AsiaChem, 2023, 3, 136.

​

31. S. Mondal, Y. Chen, G. J. Lockbaum, S. Sen, S. Chaudhuri, A. C. Reyes, J. M. Lee, A. N. Kaur, N. Sultana, M. D. Cameron, S. A. Shaffer, C. A. Schiffer, K. A. Fitzgerald, P. R. Thompson, 'Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2' Journal of the American Chemical Society, 2022, 144, 21035. 

 

30. S. Mondal, S. Wang, Y. Zheng, S. Sen, A. Chatterjee, P. R. Thompson, ‘Site-specific Incorporation of Citrulline into Proteins in mammalian cells’ Nature Communications, 2021, 12, 45. 

Behind the Paper, written by S. Mondal and P. R. Thompson.

 

29. S. Mondal, P. R. Thompson, ‘Chemical Biology of Protein Citrullination by Protein Arginine Deiminases (PADs)’ Current Opinion in Chemical Biology, 2021, 63, 19.​

 

28. F. J. Li, R. Surolia, H. Li, Z. Wang, G. Liu, T. Kulkarni, A. V.F. Massicano, J. A. Mobley, S. Mondal, J. A. de Andrade, S. A. Coonrod, P. R. Thompson, K. Wille, S. E. Lapi, M. Athar, V. J. Thannickal, A. B. Carter, V. B. Antony, ‘Citrullinated-vimentin mediates development and progression of lung fibrosis’ Science Translational Medicine, 2021, 13, eaba2927.

 

27. G. Griffante, F. Gugliesi, S. Pasquero, V. Dell’Oste, M. Biolatti, A. J. Salinger, S. Mondal, P. R. Thompson, E. Weerapana, R. J. Lebbink, J. A. Soppe, T. Stamminger, V. Girault, A. Pichlmair, G. Oroszlán, D. M. Coen, M. De Andrea, S. Landolfo, ‘Human cytomegalovirus-induced host protein citrullination is crucial for viral replication’ Nature Communications, 2021, 12, 3910.

 

26. M. T. M. Monreal, L. Massarenti, A. S. Rebak, S. Mondal, L. Šenolt, N. Ødum, M. L. Nielsen, P. R. Thompson, C. H. Nielsen, D. Damgaard, ‘Applicability of small-molecule inhibitors in the study of peptidyl arginine deiminase 2 (PAD2) and PAD4’ Frontiers in Immunology, 2021, 12, 716250.

 

25. O. Ashur-Fabian, D. Moskovich, Y. Finkelshtein, A. Alfandari, A. Rosemarin, T. Lifschytz, A. Weisz, S. Mondal, H. Ungati, A. Katzav, D. Kidron, G. Mugesh, M. Ellis, B. Lerer, ‘Targeting the DIO3 enzyme using first-in-class inhibitors effectively suppresses tumor growth: A new paradigm in ovarian cancer treatment’ Oncogene, 2021, 40, 6248-6257.

 

24. F. M. C. Sodré, S. Bissenova, Y. Bruggeman, R. Tilvawala, D. P. Cook, C. Berthault, S. Mondal, A. Callebaut, S. You, R. Scharfmann, R. Mallone, P. R. Thompson, C. Mathieu, M. Buitinga, L. Overbergh, ‘Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice’ Diabetes, 2021, 70, 516.​

 

23. Y. Tian, S. Qu, H. B. Alam, A. M. Williams, Z. Wu, Q. Deng, B. Pan, J. Zhou, B. Liu, X. Duan, J. Ma, S. Mondal, P. R. Thompson, K. A. Stringer, T. J. Standiford, Y. Li, ‘Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis’ JCI Insight, 2020, 5, e138873.

 

22. H. S. Loring, S. S. Parelkar, S. Mondal, P. R. Thompson* "Identification of the first noncompetitive SARM1 inhibitors" Bioorganic and Medicinal Chemistry, 2020, 28, 115644.

 

21. S. Mondal, D. Manna, K. Raja, G. Mugesh* "Halogen Bonding in Biomimetic Deiodination of Thyroid Hormones, their Metabolites and Halogenated Nucleosides" ChemBioChem, 2020, 21, 911.

[This article has been selected as Very Important Paper by the editors of the Journal]

[This article has been highlighted in the Cover Page of the journal]

 

20. Z. Wu, Q. Deng, B. Pan, H. B. Alam, Y. Tian, U. F. Bhatti, B. Liu, S. Mondal, P. R. Thompson, Y. Li* "Inhibition of PAD2 Improves Survival in a Mouse Model of Lethal LPS-Induced Endotoxic Shock" Inflammation, 2020, DOI: 10.1007/s10753-020-01221-0.

 

19. S. Mondal, D. Giri, G. Mugesh* "Halogen Bonding in the Molecular Recognition of Thyroid Hormones and Their Metabolites by Transport Proteins and Thyroid Hormone Receptors" Journal of the Indian Institute of Science, 2020, 100, 231.

 

18. F. Li, L. Miao, T. Xue, H. Qin, S. Mondal, P. R. Thompson, S. A. Coonrod, X. Liu, X. Zhang* "Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells" Journal of Experimental & Clinical Cancer Research, 2019, 38, 414.

 

17. S. Mondal, X. Gong, X. Zhang, A. J. Salinger, L. Zheng, S. Sen, E. Weerapana, X. Zhang, P. R. Thompson* "Halogen Bonding Increases the Potency and Isozyme selectivity of Protein Arginine Deiminase 1 (PAD1) Inhibitors" Angewandte Chemie International Edition, 2019, 58, 12476.

 

16. S. Mondal and P. R. Thompson* "Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of  Protein Citrullination" Accounts of Chemical Research, 2019, 52, 818.

 

15. S. Mondal and G. Mugesh* "Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds" Chemistry - A European Journal, 2019, 25, 1773.

 

14. S. Sen, S. Mondal, L. Zheng, A. J. Salinger, W. Fast, E. Weerapana and P. R. Thompson* "Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase" ACS Chemical Biology, 2019, 14, 613.

 

13. N. Mishra, L. Schwerdtner, K. Sams, S. Mondal, F. Ahmad, R. E. Schmidt, S. A. Coonrod, P. R. Thompson, M. M. Lerch and L. Bossaller* "Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome–Dependent IL-1β Maturation and ASC Speck Formation in Macrophages" Journal of Immunology, 2019, 203, 795.

 

12. Y. Liu, Y. L. Lightfoot, N. Seto, C. Carmona-Rivera, E. Moore, R Goel, L. O’Neil, P. Mistry, V. Hoffmann, S. Mondal, P. N. Premnath, K. Gribbons, S. Dell’Orso, K. Jiang, P. R. Thompson, H.-W. Sun, S. A. Coonrod, and M. J. Kaplan* "Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7–dependent lupus" JCI Insight, 2018, 3, e124729.

 

11. S. Mondal, S. S. Parelkar, M. Nagar, and P. R. Thompson* "Photochemical Control of Protein Arginine Deiminase (PAD) Activity" ACS Chemical Biology, 2018, 13, 1057.

[This article has been highlighted in the Front Cover Page of the journal]

 

10. V. V. Nemmara, V. Subramanian, A. Muth, S. Mondal, A. J. Salinger, A. J. Maurais, R. Tilvawala, E. Weerapana, and P. R. Thompson* "The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs)" ACS Chemical Biology, 2018, 13, 712.

[This article has been highlighted by S. Kumar in ChemBioChem]

 

9. E. F Kenny,* A. Herzig, R. Krüger, A. Muth, S. Mondal, P. R. Thompson, V. Brinkmann, H. von Bernuth and A. Zychlinsky "Diverse stimuli engage different neutrophil extracellular trap pathways" eLife, 2017, 6, e24437.

 

8. S. Mondal and G. Mugesh* "Novel thyroid hormone analogues, enzyme inhibitors and mimetics, and their action" Molecular and Cellular Endocrinology, 2017, 458, 91.

 

7. S. Mondal and G. Mugesh* "Conformational Flexibility and Halogen Bonding in Thyroid Hormones and Their Metabolites" Crystal Growth & Design, 2016, 16, 5896.

 

6. S. Mondal and G. Mugesh* "Biomimetic deiodination of thyroid hormones and iodothyronamines – a structure–activity relationship study" Organic & Biomolecular Chemistry, 2016, 14, 9490.

[This article has been selected as one of the 10 most popular articles in Organic & Biomolecular Chemistry (RSC) in the year 2016]

[This article has been highlighted in the Front Cover Page of the journal]

 

5. ​S. Mondal, R. Karuppusamy, U. Schweizer and G. Mugesh* "Chemistry and Biology in the Biosynthesis and Action of Thyroid Hormones" Angewandte Chemie International Edition, 2016, 55, 7606.

[This article has been highlighted in the Front Cover Page of the journal]

 

4. S. Mondal and G. Mugesh* "Structure Elucidation and Characterization of Different Thyroxine Polymorphs" Angewandte Chemie International Edition, 2015, 54, 10833.

[This article has been highlighted by U. Schweizer and C. Steegborn in Angewandte Chemie International Edition]

[This article has been highlighted in the Spotlights Section of Chemistry - A European Journal]

[This article has been highlighted in "The New Indian Express" Newspaper]

[This article has been highlighted​ in "Bangalore Mirror" Newspaper]

 

3. S. Mondal, D. Manna and G. Mugesh* "Selenium-mediated Dehalogenation of Halogenated Nucleosides and its Relevance to the DNA Repair Pathway" Angewandte Chemie International Edition, 2015, 54, 9298.

 

2. D. Manna, S. Mondal and G. Mugesh* "Halogen Bonding Controls the Regioselectivity of the Deiodination of Thyroid Hormones and their Sulfate Analogues" Chemistry - A European Journal, 2015, 21, 2409.

[This article has been selected as Hot Paper by the Editors of the journal]

 

1. S. Mondal and G. Mugesh* "Regioselective Deiodination of Iodothyronamines, Endogenous Thyroid Hormone Derivatives, by Deiodinase Mimics" Chemistry - A European Journal, 2014, 20, 11120.